Yes, The Best, Just Got Better!

Never a company to rest on its laurels and always pushing the boundaries of human performance enhancement through sports supplementation to the absolute limit, BSN has remained committed to innovation, and to producing the best products in the world for the last 7 years. Over the course of those 7 years, BSN has carved out its own unique position as the sports nutrition industry’s ultra-premium brand with products relied on by a who’s who of the bodybuilding, fitness and sports world. The likes of 8-Time Mr. Olympia and the world’s greatest bodybuilder Ronnie Coleman, cover model and TV personality Alicia Marie, the “PHENOM” and future of bodybuilding Trey Brewer, genetic wonder Brandon the “PRODIGY” Curry, pro martial artist/actor Julien Greaux, U.S. Masters National Champion cyclist Antony Galvan and professional beach volleyball player Ty Loomis all rely on BSN products to do what they do best – Finish First™! BSN’s place atop the sports nutrition mountain is further exemplified by BSN’s recognition as the 27th fastest growing private company in America and showcased by the fact that the BSN brand, labels, advertising and most notably, its products have won numerous consumer-voted sports nutrition industry awards over the course of the last three years, including an unprecedented, and industry high 7 awards in 2007. This was all made possible because of BSN’s position at the forefront of industry development and a relentless commitment towards producing the most novel physique and performance enhancing supplements for athletes. It’s this same position on the cutting-edge and adherence to the same never-ending commitment to push the envelope of human performance to its absolute human limit that has led to the development of BSN’s newest breakthrough milestone innovation, the AVPT Multi-Action Matrix.

AVPT is an acronym that stands for Advanced Volumizing & Performance Technology. This multi-action matrix is made up of a unique combination of amino acids, cooperative creatine analogs and critical muscle growth mediating bio-factors, all designed to support and enhance:

• Increased energy production
• Superior nutrient transport and saturation into muscle tissue
• Improved nutrient absorption and assimilation
• Accelerated blood flow
• Increased strength levels
• Enhanced muscle growth
• Heightened cell volumization and vascularity
• Better muscle pumps
• Improved workout performance
• Increased peak torque performance
• Greater muscle recovery

This amazing AVPT Multi-Action Matrix has now been built and electro-charged into BSN’s flagship Core Series products; N.O.-XPLODE™, CELLMASS® and NITRIX®, thereby making these industry leading products even better by dramatically heightening their ergogenic effectiveness. Once again, BSN has stepped up to the plate, delivering the most up to date envelope-pushing human performance enhancement for 2008! Check your local retailers for the new and improved AVPT Multi-Action Matrix containing N.O.-XPLODE™, CELLMASS® and NITRIX®!!

BSN products N.O.-XPLODE™, CELLMASS® and NITRIX® have now been electro-charged with AVPT Multi Action Matrix, making them new and improved – thereby dramatically heightening their already amazing effectiveness!

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Feel bright, alert and focused
When describing the 5-Hour Energy feeling, some people say it’s “like the sun coming up in my head.” That’s because when you’re feeling groggy and lethargic, 5-Hour Energy wakes up your brain and gets you back to feeling the way you want to feel – bright, alert, focused and energetic. What you won’t feel is jittery, or – crash*. That’s because, unlike other energy drinks, 5-Hour Energy doesn’t jack you up with sugar, caffeine and herbal stimulants. Instead, it’s packed with stuff that’s good for you – B-vitamins, and amino acids.

Drink it in seconds
To get anything out of those canned energy drinks you have to force down a lot of liquid – up to 24 ounces for some of them. It takes just seconds to slam down a 2-ounce 5-Hour Energy shot. That means its energizing ingredients get into your system faster.

Feel it in minutes
In a few minutes you can feel 5-Hour Energy brushing away the cobwebs and helping you regain the alert, focused feeling you need to get through your day. Canned energy drinks give you a lot of sugar, caffeine and herbal stimulants which can make you feel jittery, shaky or tense. But 5-Hour Energy’s blend of vitamins, and amino acids gives you hours of “smooth energy.”

Lasts for hours with no crash*
We named it 5-Hour Energy for a reason. People typically feel an elevated sense of energy, focus and alertness for about five hours. Individual results will vary, of course. And when that feeling wears off, it does so gently. Other energy drinks can make you feel jittery and tense for a short time then let you down with a crash* leaving you feeling worse than before.

What to Expect from 5-Hour Energy
If you’re not tired, why take an energy drink? 5-Hour Energy was designed to be functional, not recreational. It will take you from tired and foggy to bright and focused. But it won’t take you beyond that.

Afraid to try 5-Hour Energy?
You may have read some scary things about other energy drinks and are afraid to try 5-Hour Energy. The knock on other drinks is their large amounts of sugar, caffeine and herbal stimulants such as guarana and ginseng. But 5-Hour Energy contains no sugar, no herbal stimulants and only as much caffeine as one cup of coffee. The active ingredients in 5-Hour Energy can be obtained in everyday foods, or is a nutrient your body makes naturally.

5-Hour Energy Ingredients

Compare 5-Hour Energy with a popular canned energy drink. You’ll see that 5-Hour Energy contains more of what you want and less of what you don’t want in an energy drink.

5-Hour Energy Convenience

When it comes to convenience, 5-Hour Energy has it all over canned energy drinks. While they go bigger and bigger – as much as 24 ounces – 5-Hour Energy is only two ounces. Think about it – you get more energy and have less to drink. That means the energizing ingredients get into your system faster. It also means you don’t have to carry a big can of sugary soda with you.

5-Hour Energy Vitamins

Vitamin B6
Vitamin B6 was first researched in the 1930’s. Its original name was “antidermatitis factor” because skin inflammation seemed to increase when foods with vitamin B6 were absent from the diet. It is difficult to find a molecule in our bodies that doesn’t rely on vitamin B6 for its production. It plays a key role in the production of amino acids, the building blocks of protein. It is used in the creation of DNA. It’s involved in over 100 crucial chemical reactions in our bodies. It helps form nearly all new cells in our bodies.

Here is a brief list of the other things vitamin B6 does:

• Helps our nervous system function properly.
  
• Required for the production of hemoglobin, the compound in red blood cells that transports oxygen and carbon dioxide.
  
• Increases the amount of oxygen carried in our blood.
  
• Helps maintain a healthy immune system.
  
• Aids in the processing of carbohydrates for energy.
  
• Food sources of vitamin B6 include fortified cereals, beans, meat, poultry, fish, and some fruits and vegetables.

Vitamin B12 (Cobalamin)
Two Nobel Prizes have been awarded for research involving the study of vitamin B12. Like other B-complex vitamins, vitamin B12 is involved in a variety of important functions. Perhaps its most important function is the development of red blood cells. Another is the development of nerve cells. B12 also participates in the production of amino acids, and the processing of carbohydrates into energy.

Niacin (Vitamin B3)
The first laboratory isolation of vitamin B3 occurred during research studies of tobacco in the 1930s, hence niacin is also known as “nicotinic acid.” Niacin is important in energy production. It plays a key role in converting fats, proteins, carbohydrates and starches into usable energy. It also helps remove toxic chemicals from the body, and has been shown to increase the level of HDL (good cholesterol) in the blood. Because niacin opens capillaries and increases blood flow near the skin, elevated doses can cause skin flushing in some people. This is characterized by a red and itchy face and neck that lasts a few minutes. (A form of niacin called niacinamide causes little or no flushing.) Food sources of Niacin include: meat and dairy products, leafy vegetables, broccoli, tomatoes, avocados, nuts and whole grains.

Folic Acid (Vitamin B9)
Folate gets its name from the Latin word “folium” for leaf. A researcher in the 1930’s discovered that anemia of pregnancy could be corrected by a yeast extract. The active ingredient in this process was later identified as folate, and was extracted from spinach leaves in 1941. Folic acid, or folate, helps produce and maintain new cells in our bodies. It’s also needed to make DNA and RNA, the building blocks of cells. It works with vitamins B12 and vitamin C to break down proteins and form hemoglobin. It’s very important in pregnancy and preventing birth defects. Folic acid deficiency has been linked with irritability, mental fatigue, forgetfulness, confusion, depression, muscular weakness and insomnia. Food sources of folate include leafy green vegetables, fruits, dried beans and peas.

5-Hour Energy Energy Blend

• Citicoline (as of October 2007)
  
• Supports healthy cognitive function.
  
• Maintains healthy memory and thinking ability.
  
• Protects healthy brain cell function.
  
• Sustains healthy cell membranes in the brain.
  
• Helps brain cells communicate by keeping cell membranes in good condition.

Citicoline has been used extensively for the promotion of optimal neural and cognitive function and has been shown to be useful in promoting normal healthy brain aging. The human brain is a delicate organ of the body, constantly being attacked by various factors in our lifestyles including environmental pollution, internal toxicity, stress and a lack of proper diet and nutrients. Citicoline may help combat the ravages of these effects by stimulating the nervous system to maintain optimum sustainability to preserve our ability to think cognitively and retain our memories. There have been many studies citing positive results for using Citicoline to improve performance and memory. Numerous scientific studies have also indicated the ability of Citicoline to maintain healthy cognitive function as we age, promote optimal visual function and protect neural structures from free radical damage.

Tyrosine
An amino acid that transmits nerve impulses to the brain, elevates mood, improves memory and increases mental alertness. It’s present in meat, dairy, fish and grains.

Phenylalanine
An essential amino acid that elevates the mood, enhances memory, alertness and learning and suppresses the appetite. It’s found in dairy products, avocados, legumes, nuts, leafy vegetables, whole grains, poultry and fish. Click here to read more about phenylalanine.

Taurine
A naturally occurring chemical substance present in meat, fish and dairy products. Vitamin B6 is required by the body to synthesize Taurine from other nutrients. Adult humans have high concentrations of Taurine in white blood cells, skeletal muscles, the heart and central nervous system. It plays a role in digestion, and is used to process potassium, calcium and sodium in the body, as well as maintain the integrity of cell membranes.

Malic Acid
A naturally occurring chemical our bodies require. It is a biochemical product of the Kreb’s Cycle, a chain of reactions involved in the production of cellular energy. The body synthesizes Malic Acid during the process of converting carbohydrates to energy. It also helps remove high levels of phosphorous and aluminum from the body. The main food source of Malic Acid are fruits, especially apples, which contain the highest concentrations.

Glucuronolactone
A natural metabolite found in the human body. It is produced by the metabolization of glucose in the liver, and has been clinically shown to reduce sleepiness and sleep-related traffic accidents. It is widely known to improve mental performance, reaction time, concentration and memory.

Caffeine
Provides a boost of energy and feeling of heightened alertness. Caffeine also facilitates the rapid absorption of nutrients, including B-vitamins. 5-Hour Energy contains caffeine comparable to a cup of the leading premium coffee. Limit caffeine products to avoid nervousness, sleeplessness, and occasional rapid heartbeat.

Phenylketonurics
“Phenylketonurics: Contains phenylalanine.” This scary sounding warning has given phenylalanine a bad rap among those with imaginations that run toward conspiracy theories. What’s a phenylketonuric? What’s a phenylalanine? Why am I in danger from it?

The answers are simple. Phenylalanine is an essential amino acid (must be acquired in food) that is used by the brain to produce norepinephrine, a chemical that transmits signals between nerve cells and the brain; keeps you awake and alert; reduces hunger pains; functions as an antidepressant and helps improve memory. It is present in nearly all foods containing protein. Phenylketonurics are people that have a genetic disorder called phenylketonuria (PKU). People with this disorder are unable to metabolize phenylalanine and must adhere to a low protein diet and abstain from foods containing phenylalanine. Babies are tested for PKU at birth so if you have it you already know it. If you never heard of PKU, don’t sweat it. Your doctor figured it out for you years ago.

It’s the presence of phenylalanine in the artificial sweetener aspartame (e.g. Equal, NutraSweet) that has spawned these warnings and suspicion of phenylalanine. Aspartame is used to sweeten many sugar free beverages and chewing gums. But the amounts of phenylalanine in aspartame are an incredibly low risk factor. Far larger quantities of phenylalanine would be obtained by consuming most protein rich foods. Please note: 5-Hour Energy does not contain Aspartame.

Large amounts of vitamins
5-Hour Energy contains large amounts of B Vitamins. These vitamins are water-soluble which means that which is not absorbed by the body is simply expelled with no toxic effects. In fact, people on Vitamin B therapy from a doctor receive much larger doses than the amount in 5-Hour Energy.

Niacin flush
A small percentage of people are sensitive to Niacin (Vitamin B3) and may experience a “Niacin Flush” (hot prickly feeling, skin redness) that lasts a few minutes. This is caused by Niacin increasing blood flow near the skin. This can be avoided by taking half a bottle or less at a time.

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As many of you know the Venom 3.0+ has been on backorder for a long time from ALRI but we finally got this in stock and all backorders are shipping out. We also have TONS in stock now and Guarantee that your order for Venom 3.0+ will ship today! http://mysupplementstore.com/venombyalri.html 

Venom Hyperdrive 3.0 by ALRI Item# MSS-0751 Retail Price: $74.95 Our Price: $31.95 You Save $43.00 Cost/Serving $0.35 90caps 90 servings Availability Usually ships the next business day.   Not sure if this supplement is right for you? Click here to see our Best Selling Supplements List! send this page to a friend and receive 5% off this order! Click here send now!

Description Shipping Info You may also like Why Buy from My Supplement Store? Venom Hyperdrive 3.0 by ALRI Increases Stamina And Energy While Suppressing Appetite! At last a fat loss supplement you can actually feel within the very first hourof taking the very first dose. By creating a pro-energy fat mobilizing structure that supports the body’s ability to utilize fat as a source of energy (Calorie expenditure), ALRI has set a new standard for energy and fat loss supplements. Why do almost all fat loss systems fail? It’s pretty simple really. Come on now. Everyone wants to see what’s under that extra fat layer, but when we first start dieting (restricting our calorie intake) and augment the amount of calories we burn (by increasing exercise), everything goes great for about the first week. Then, like most human’s on the planet, we start getting hungry (like eating a whole wedding cake at 3 AM type hungry) and run out of energy. So, in short, you crave food and have no interest in doing anything that requires any energy unless it somehow involves that wedding cake and a gallon of milk. (ya, I know, no fat people jokes) So What Do We Need To Succeed? First, we need to clean up our diets by dropping sugars, alcohol, and excessive fatty foods (Okay, at least consume them only in moderation). Second, we need to put together a training program that increases the number of calories we burn per day. Third, we need to do something about that “Commit felonies for a wedding cake but too lazy to do so” feeling that always hits us like a ton of lard after the first week of lower calories! Lastly, we need something to bolster the increased metabolic rate (increased calorie expenditure) we generated while training our ass off because it certainly would make the whole deal more worth while, right? Venom from ALRI is a supplement designed for adults age 21 or over only. This is a product created for those adults who need the best environment to achieve results through responsible application of a highly advance formula in combination with hard training and smart nutrition. Venom is specifically formulated using the only the most effective metabolic support compounds. Additionally these compounds were specifically chosen both for their own unique affects, and for their profound synergy so 1 + 1 =3. This product has been reported to: Increase stamina and energy Manage appetite Increase calorie expenditure Improve long term performance Improve mental focus Serving Size: 1 Capsule Servings Per Container: 90 Amount Per Serving: Unique Proprietary Matrix: 300mg Cocoamine, Guarana extracts,Hoodia gordonii, 5-HTP, ALAVitaberine (thiamine trisulfide analog), B-12 (as cyanocobalamin), Guggul Extracts (2.5% Guggulsterones),Rhodiola rosea root extract, Capsiate. Inactive Ingredients: Magnesium stearate, maltodextrin and gelatin capsule. Directions: As a supplement begin by taking one (1) capsule firth thing in the morning with food for first 2 days before progressing to one to two (1-2) capsules one to two (1-2) times daily. Always take this supplement with food and do not exceed recommended supplemental dosages.

Post Cycle Therapy – KickStart Libido – Optimize Cycle Bridging

Attention Pro-Hormone Users- URGENT INFO
Order PCT MaXX Today… You’ll be glad you did!!

Attention Pro-Hormone Users- URGENT INFO about your cycle!! What’s the most common complaint of any pro-hormone user today- easy! “Why don’t my gains last once I’m off cycle!!” I’m sure you have either thought this or heard someone say this over the years. Well, I’m here to tell you that it isn’t the pro-hormones fault – it’s your fault! Ok, no need to get upset at me for saying that, it’s EASY to fix. After you go off cycle if you aren’t using a good Post Cycle Therapy stack or PCT then you are just throwing away your cycle and all or most of your gains!

Now, most PCT supplements use fancy 13 syllable ingredients that, well to be honest sound great but who really knows if they work. I mean they have only been around for a few weeks or months so there isn’t any hard data or factual information about their effectiveness. Well, once again NRG-X Labs has done something about this… in a world of WAY over hyped supplements PCT MaXX is built on solid testosterone boosting ingredients that (A) you can actually pronounce, (B) that you have probably heard of before and (C) that have been around and been used for PCT work since Arnold was lifting!!

Read below about the PCT MaXX and then GET A BOTTLE today so that once you’re off cycle you can keep you gains and keep growing!! Be a monster today and for a long time to come, not just for the 12 weeks you’re on cycle.

I believe in PCT so much that I’m offering a 20% coupon if you just order PCT MaXX today and give it a try, it’s so safe and effective many clients of ours use it during their cycle as well as after their cycle to boost testosterone production while they are on cycle! Use coupon code GETPCT today and we’ll take 20% off – stock up cause this offer is only good for a few days!
—————————-
PCT MaXX by NRG-X Labs
PCT-MAXX Amplifier is a function specific formula created to regulate hormonal levels after doing any androgenic/ anabolic cycle. Pro Hormones can and will cause an imbalance in your body’s natural production of testosterone. To bridge and support your natural testosterone levels and retain the hard earned muscle and “kick” libido into hyper drive. The time following your cycle is the most crucial as having a lack of production of testosterone in your body is why most lose their muscle gains following any androgenic or anabolic cycle. PCT-MaXX was engineered to provide the necessary nutrients required for the bridging process and balance your natural hormonal levels and support an anabolic environment.

PCT-MAXX Amplifier Ingredient Profile:

Eurycoma Longfolia:
The British Journal of Sports Medicine published the results of a scientific study in 2003, which showed that Eurycoma longifolia caused increased muscle strength and size when compared to a placebo. This may demonstrate the anabolic properties of Tongkat Ali many athletes and bodybuilders now use Tongkat Ali extract as a testosterone-booster, to improve muscle size, strength, and performance without drugs. Eurycoma longifolia has become popular for its testosterone-enhancing properties. Historically, South East Asia has utilised the herb for its suggested antimalarial, antipyretic, antiulcer, cytotoxic and aphrodisiac properties. Scientific studies suggest that it enhances sexual characteristics and performance in animals.

Epimedium Sagittatum (AKA – Horny Goatweed):
Many species of Epimedium are alleged to have aphrodisiac qualities. According to legend, this property was discovered by a Chinese goat herder who noticed sexual activity in his flock after they ate the weed. Like Viagra, icariin works by increasing levels of nitric oxide, which relax smooth muscle. It has been demonstrated to relax rabbit penile tissue by nitric oxide and PDE-5 activity!

Tribulus terrestris:
Tribulus terrestris has long been a constituent in tonics in Indian ayurveda practice, where it is known by its Sanskrit name, “gokshura.” It is now found to be a booster for the purpose of increasing sex drive. Its use for this purpose originated in Eastern Europe in the 1970’s. Independent studies have suggested that Tribulus terrestris extract increases hormone levels, though leaving them in the normal range.

Plus… Gamma Aminobutyric Acid (GABA), Yohimbe Extract and Cnidium Monneri

Supplement Facts
Servings per container: 30
Serving Size:3 capsule
Amount per serving

Niacin …………. 90mg..
Pyridoxine Hydrochloride…………21mg..
PCT-MAXX Amplifier…………………….. 1990mg

Tribulus terrestris (60% Saponins), Yohimbe Extract (8% Yohimbine), Maca Root 4:1 (Lepidium Meyenii), Epimedium Sagittatum Extract 4:1 (Bark), Eurycoma Longfolia (20:1) L-Arginine Alpha Keto-Gluterate, Avena Sativa Extract (Standardized For Avenacosides A&B), Gamma Aminobutyric Acid, Cnidium Monneri (4:1) fruit

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Over the past nine years, I have worked with the top researchers, pharmacologists, and physicians from Hi-Tech Pharmaceuticals to develop the perfect diet pill. Hi-Tech has put out several blockbuster weight loss aids such as Lipodrene®, Stimerex-ES®, and Lipodrene Xtreme®, to name a few. One thing most people do not know about Hi-Tech is its direct response business. Over the past ten years, Hi-Tech has had three weight loss sister companies that formulate, market, and sale diet aids direct to the public. “So what?” you may ask. Well, Hi-Tech offers a 100% money-back guarantee to anyone not satisfied. Hi-Tech marketed over 20 diet aids with different ratios of ingredients until it hit pay dirt. Hi-Tech sold direct to over 500,000 consumers and was able to track refund rates and compare them versus re-order rates. Lipodrene® and Stimerex-ES® were launched by Hi-Tech to retailers as they were the two best products Hi-Tech developed out of the 20 test marketed. No other company has the data, feedback, or technology to create such products. With the evolution of Hi-Tech’s pharmacological research into weight loss compounds, I believe we have created our finest masterpiece!

As a bariatric (weight loss) physician, I prescribed Fastin™ for decades as a prescription drug to my patients with overwhelming success. When SmithKline Beecham (now known as GlaxoSmithKline) withdrew Fastin™ from the market, it sent shockwaves through the weight loss industry. Since its exit from the market, Hi-Tech has been doing some exhaustive research and development on a new formula with pharmaceutical fat mobilization and apoptosis agents to create the new and improved Fastin™. Fastin’s effectiveness produced an almost cult following, Fastin™ was unmatched in its efficacy until it was taken off the market by GlaxoSmithKline. Unwilling to attach the name “Fastin” to just any ole fat burning fat burning formula, Hi-Tech has spent a countless amount of time and resources to find a formula equal to or superior to the original Fastin, in terms of feeling and effect. Finally, after several years of research on this project, Hi-Tech developed a formula that is every bit as good (if not better) than the original Fastin formula. Hi-Tech is so confident in Fastin that they are staking their name on it in many ways as the leaders in the weight loss industry…as the shoes Hi-Tech had to fill were very large.

Although the feeling and effect of Hi-Tech’s Fastin™ is at least as good as the original, the formula has changed in significant ways. The old Fastin formula was formulated around Phentermine HCL, while the new Fastin is formulated around phenylethylamine HCL and derivatives of this molecule. Phenylethylamine is an amazing compound that is naturally present in human fluids and tissue. This compound is probably the cleanest stimulant ever researched, which has the remarkable ability to stimulate the central nervous system, without causing nervousness or the jittery feeling. Phenylethylamine is found in chocolate and is responsible for its effects on mood, appetite, and sense of well-being.

Fat mobilization is a new breakthrough in the field of weight loss. As a bariatric physician (weight-loss physician), I try to stay at the forefront of the diet industry. The newest thermogenic breakthrough introduced into the market is called Lipid Mobilization, which helps you burn body fat without exercise. In vitro research shows that lipid mobilization is one of the processes that releases fat into the bloodstream to be burned as energy. On the fat cell’s surface are receptors that signal the cell to hold stored fat. Natural Alpha-2 antagonists have been shown to switch off these receptors. Freed fatty acids can then move out of the cell and into the bloodstream. These released fats are shuttled away from fat and prevented from simply being re-deposited. This is especially effective in the stubborn abdominal and hip areas of both men and women. Best of all, when taken before exercise, fat mobilizers are shown to boost lipolysis (the process of mobilizing fats from cells) and increase blood serum free fatty acid levels both during and after exercise.

The extent of which exercise burns body fat is totally dependent upon the rate of lipolysis. Lipolysis is the rate at which fat is mobilized from fat cells and enters the bloodstream as free fatty acids (FFAs). Exercise triggers lipolysis, and highly trained individuals possess a greater lipolytic rate, an ability to “burn” more fat during exercise, than untrained people. If you want the greatest possible fat-burning effect from exercise, then increasing your rate of lipolysis is the way to do it. A high rate of lipolysis ensures greater fat mobilization by the liver and mitochondria in muscle cells during exercise. In turn, this process ensures that a greater concentration of body fat is burnt during exercise. The impact of fat mobilizers on post-exercise fat metabolism is particularly evident 30 minutes after cardio exercise. One study showed that FFA levels in the bloodstream doubled in those that took a fat mobilizer prior to exercise compared to a placebo.

Many physiological factors stimulate and inhibit the breakdown of adipose tissue into free fatty acids and glycerol and their mobilization into the bloodstream to be used as fuel by other cells and tissues. Fasting, feeding, exercise, and stress have pronounced and rapid effects on lipolysis via hormones and other endogenous substances. As well, clinical conditions such as diabetes and obesity are associated with alterations in lipolysis. Age and gender are also of importance.

Insulin and catecholamines are the main regulatory hormones of lipid mobilization. Insulin is the major antilipolytic hormone because of its effects on enzymes within the adipocyte. Insulin also enables the entry of glucose into the cells by inducing glucose transporter activity. Glucose serves as the backbone for the glycerol molecule to which fatty acids attach and form triacylglycerols. The catecholamines serve a dual function. You must first become acquainted with fat cell biology to comprehend the regulation of fat loss. Lipogenesis and lipolysis can be considered the Yin and Yang of adipose tissue metabolism. Lipogenesis is the process of fat accumulation and lipolysis is that of fat breakdown and release into the bloodstream.

There are physiological differences in fat cells, depending upon where they are located in the body. Fat cells located in the gut (visceral adipocytes) differ from fat cells located in the lower regions of the body (hips, thighs, lovehandles). Fat cells within the stomach contain a lot of beta-receptors. These cells respond to release fat when stimulated by the classic “fat-burners,” such as caffeine, ephedrine, and synephrine. These compounds stimulate lipolysis specifically by increasing norepinephrine delivery to the visceral fat cells and catecholamine secretion that activates the beta-receptors and increases CAMP within cells. However, fat cells located around the hips, and lovehandles characteristically contain very few beta-receptors and respond poorly to catecholamine release that is induced by exercise and beta-stimulants. However, these lower body fat cells contain a lot of alpha adrenoreceptors. Alpha-receptors are tricky and obstinate if you want them to release their fat stores. When stimulated, these receptors activate other proteins that inhibit adenylcyclase, thus antagonizing the ability of beta-adrenoreceptors to boost CAMP generation, and therefore, shut down the usual fat mobilization process. Basically, when taking caffeine, ephedrine, and synephrine supplements in an effort to stimulate fat loss, the alpha-receptors on lower-body fat cells say “No! No fat mobilization for you!” Fat cells within the lower half of the body contain a higher concentration of alpha-receptors and lower concentration of beta-receptors. Therefore, they are quite resistant to lipolysis. Women characteristically carry more fat on their hips and thighs than men do, and this difference in fat cell structure is one reason why most women have a tougher battle with fat loss…Until Now!

Hi-Tech has recognized for years that the active components in Hi-Tech’s fat loss products exerted their influence on fat loss through mechanisms of action attributable to increased lipolysis, decreased Lipogenesis, and more metabolically desirable fat mobilization. However, over the past five years of Research and Development, Hi-Tech began testing a theory that some of the beneficial effects of Lipodrene® and Stimerex-ES® were also actually due to their effect on elimination of entire fat cells, or apoptosis. Apoptosis is a form of cell suicide that plays a vital role in the maintenance of cellular homeostasis, but for weigh loss it causes cell death (specifically, fat cell death). It was once believed that the total number of adipocytes (fat cells) remained fairly constant over one’s lifetime; however studies over the last ten years have shown that adipocytes can be both lost and gained, and it is becoming increasingly recognized that fat cells have a finite life cycle and can be eliminated by apoptosis.

Apoptosis is a novel approach to help people lose fat. Since research began several years ago on this activity of the compounds in Lipodrene®, Hi-Tech has been investigating many plant extracts and other natural substances for their ability to reduce adipose tissue mass by reducing the number of adipocytes through the mechanism of apoptosis. We have identified a number of agents that may induce apoptosis of adipose tissue, and found that some catecholamines and beta-adrenergic receptor agonists are prone to induce adipose tissue apoptosis when administered orally. These compounds include: clenbuterol, ractopamine, phenylethylamine, and alkaloids from acacia rigidula extract, including b-phenylethylamine, N-Methyl-b-phenylethylamine, and R-beta-methylphenylethylamine. These compounds appear to have the ability to increase the rate of apoptosis in adipose tissue cells, specifically white adipose tissue cells. It is suggested that Fastin’s active components demonstrate a wide array of action on adipocytes, including increased lipolysis, decreased Lipogenesis, decreased cell proliferation, and increased adipogenesis (blocking immature fat cells from maturing and storing lipids). In addition, Fastin assists in more effective lipid mobilization.

Fastin brings forth a trifecta of advancements in the fat loss arena: 1) a sophisticated manufacturing process that utilizes a dual delivery system technology for specific control of rapid and sustained release of its active compounds, 2) a proprietary active compound formulation that trumps the existing field of fat loss compounds and puts even ephedra in the back seat, 3) a novel approach to fat loss through triggering fat cell death (apoptosis).

Hi-Tech Pharmaceuticals recently launched Fastin™ into the weight loss arena. In recent months, Hi-Tech acquired rights to Fastin from King Pharmaceuticals. King Pharmaceuticals manufactured the brand name product Fastin (phentermine HCL) for Smith Kline Beecham. In December 1998, SK-Beecham withdrew Fastin from the market. Hi-Tech Pharmaceuticals has reformulated Fastin and expects it to be their top weight loss aid. Fastin is a pharmaceutical-grade dietary supplement indicated for weight loss in extremely overweight individuals. Fastin has booth immediate and delayed release profiles for appetite suppression, energy, and weight loss. Fastin is comprised of nine pharmaceutical-grade fat loss catalysts at precise ratios in order to achieve its extraordinary results. Fastin’s proprietary formula includes the following

R-Beta-methylphenylethylamine HCL – this amazing compound is the active isomer of MPEA much like 1R, 25 Norephedrine was of PPA years ago. This compound stimulates norepinephrine unlike any other and leads to appetite suppression, energy, and ultimate fat loss.

Methylphenylethylamine tartrate – this is the racemic version of MPEA bound to tartaric acid, which keeps the molecule stable. This compound is found in Hi-Tech’s line and is a rising star of the fat loss industry.

N-methyl-phenylethylamine – is another isolated amine from acacia rigidula that is both for stimulating fat burning and energizing effects. This is the N-methyl derivative of the compound B-Phenylethylamine. This is a very potent compound for all who lack a chemistry degree

Methylsynephrine – is phenolic B-Phenylethylamine found in Acacia Rigidula and some cacti, which produces considerable nervous system stimulation (CNS). With Hi-Tech’s research over the past five years on Acacia Rigidula (as Thermo-Rx®), we have identified and isolated several key phenylethylamine alkaloids. The newest of which is methylsynephrine. The alkaloids from the acacia rigidula are biologically and physiologically similar to those found in ephedra, and possess properties that are shared with ephedra alkaloids. Scientifically, this is in part due to the similarities in pharmacokinetics and pharmacodynamics. The most obvious similarity is that acacia alkaloids, like the ephedra alkaloids, readily pass into the brain. The main factor governing the transfer of small molecules into the central nervous system is lipophilicity. The distribution of drugs and/or compounds into the CNS from the blood is unique, because functional barriers are present that restrict entry of drugs into this critical site. One reason for this is that the brain capillary endothelial cells have continuous tight junctions; therefore, drug penetration into the brain depends on transcellular rather than paracellular transport between cells. The unique characteristics of percipaillary gilial cells also contribute to the blood-brain barrier. At the choroids plexus, a similar blood-cerebrospinal fluid (CSF) barrier is present, except that it is epithelila cells that are joined by tight junctions rather than endothelial cells. As a result, the lipid solubility of the nonionized and unbound species of the drug is an important determinant of its uptake by the brain; the more lipophilic it is, the more likely it is to cross the blood-brain barrier. This situation is used in drugs design to alter the brain distribution, which is the case with drugs like amphetamine, phentermine, and benzphetamine. As you can see from the comparison of the structures of ephedrine, norephedrine, and methylsynephrine they all possess the b-methyl substituent of the aliphatic sidechain, which is characteristic of ephedrine and its congeners, as well as methylsynephrine, thus further increasing lipophilicity.

What is a suitable substitute for ephedra? How about another beta agonist? Methylsynephrine is just the answer that the industry has been waiting on for years! The sympathetic nervous system is involved in the regulation of energy. Therefore, pharmacological manipulation of the system offers a mechanism of targeting a reduction in excess body fat stores. Many beta-adrenergic agonists are known to increase muscle mass while concurrently decreasing fat mass. Prolonged treatment with sympathomimetic compounds reduces energy intake and increases energy expenditure. The beta 2&3 receptors appear to be responsible for the lipolytic and thermogenic effects of adrenergic agents, while interaction with beta-1 and to a much lesser extent, beta-2 control cardiac effects. Accordingly, the ideal fat loss compound would be one identical to acacia rigidula and especially methylsynephrine. Until now, there has never been a beta-adrenergic compound like methylsynephrine that can stimulate lipolysis and increase resting metabolic rate like ephedra.

Theobromine – is the primary methylxanthine found in products of the cocoa tree, Theobroma cocao. As a member of the methylxanthine family, it is thought to elevate levels of serotonin, the same action as the popular anti-depressants. Theobromine has a lot of research that shows its extraordinary effects on fat loss, appetite suppression, and mobilization of fatty deposits. Theobromine acts as a mild diuretic and stimulant, which creates a synergistic effect with caffeine.

Phenylethylamine HCL – this amazing compound is probably the cleanest stimulant ever researched, and it is naturally present in human fluids and tissues. Although categorized as a stimulant, it has the remarkable ability to simulate the central nervous system without causing nervousness or the jittery feeling. Phenylethylamine is found in chocolate and is responsible for its effects on mood, appetite, and sense of well-being. Until recent discoveries, PEA, or phenylethylamine, was rapidly destroyed within the body. If included with novel delivery systems, phenylethylamine HCL is provided “safe transport” and this metabolic fate is avoided and pharmacological activity becomes extremely apparent. This catecholamine precursor is responsible for elevating the metabolic rate and promoting a sense of satiety. Phenylethylamine acts on alpha-receptors in the brain, as do norepinephrine and certain prescription anti-obesity drugs. It is also believed to cause the release of dopamine in the pleasure sensing areas of the brain. Phenylethylamine HCL has a close chemical relationship to pharmaceutical stimulants, because it is the “backbone” of many pharmaceutical compounds.

Yohimbine HCL – has been shown in many clinical trials to effectively block alpha 2 adrenoreceptors. These studies have found that yohimbine increases the amount of non-esterfied fatty acids (NEFA’s) a product of lipolysis (the breakdown of fat), in the blood-stream for both lean and overweight subjects. There are a number of feedback mechanisms that prevent the release of norepinephrine (NE), one of the body’s primary lipolytic hormones. When NE is released, such as when taking methylsynephrine and acacia rigidula, it stimulates both the alpha and beta adrenoreceptors. Stimulation of the beta adrenoreceptors has the opposite effect, preventing the release of NE and lipolysis. Yohimbine prevents this negative feedback mechanism, and works in a synergistic fashion with the other components to increase NE and lipolysis. There are a number of reasons why alpha-2 inhibition is specifically useful. First, while the beta-adrenergic system primarily controls lipolysis during periods of intense activity, during rest, which makes up most of our day, the alpha-adrenergic system is in control. Also, “stubborn fat” areas – usually the abdominal area in men and the glutofemoral area in women – contain a higher ratio of alpha-2 receptors, making yohimbine particularly effective in these areas (whereas other drugs that increase NE may be somewhat counterproductive). Finally, alpha-2 blockade increases blood flow in adipose tissue, which prevents fat from being retained in the area.

Synephrine HCL – is a drug used primarily in fat loss, although the effectiveness is minimal in Fastin. It is very popular and has been used as an alternative to ephedrine (a substance with a history of controversy). Synephrine is derived primarily form the fruit of a small citrus tree.

Caffeine Anhydrous USP – acts as a stimulant and thermogenic in humans, and is commonly taken to boost energy or mental concentration. It will stimulate the central nervous system and the metabolism. Once metabolized, caffeine can increase lipolysis in the body. Caffeine may also increase the effectiveness of other substances such as ephedrine or yohimbe, and was incredibly popular in the commonly used ECA stack (ephedrine, caffeine, and aspirin).

In Romeo and Juliet by Shakespeare, the character, Juliet says, “What is in a name? That which we call a rose by any other name would smell as sweet.” Hi-Tech has attached the name, Fastin, to the most effective diet aid of the 21st century. Hi-Tech expects to revive the cult following that Fastin previously enjoyed. Hi-Tech also enjoys the challenge of living up to a legend. In baseball, Ken Griffey, Jr. came into the league with big shoes to fill in his hall of fame father’s Cincinnati Red eyes. Today, 593 home runs later, “the natural,” as many call him, feels he achieved quite a bit more than his father ever did in baseball, and did more than just fill his father’s shoes. In NASCAR racing, Dale Earnhardt, Jr. has fans worldwide expecting him to continue winning and live up to his father’s reputation – which is that he was the best driver to ever get behind the wheel of a car. Fastin by Hi-Tech Pharmaceuticals not only welcomes the challenge of living up to a legend, but chose the name in order to have a tell set of shoes to fill. Fastin is a world class fat burner that will help anyone needing to lose weight. Whether you need to lose a little or a lot of weight – Fastin is just what the doctor ordered!

A Utah state court judge declared the FDA ban on Ephedra, Ma-huang, as a drug wrong on April 14th 2005. The FDA filed an appeal to have the ruling overturned in a higher court. The appeal was granted and the ruling was overturned as of August 18, 2006. This means the FDA is entitled to pose restrictions and/or limitations on sales of pills with Ephedra. However, the FDA won’t be allowed to write their own restrictions as they have done in the past. Any restrictions would be presented via a proposal. That proposal would then have to be voted on and passed through both the House of Representatives as well as the Senate.

So the question for the general public still remains,”Is ephedra legal?” For now, the future availability of ephedra in the U.S.A. is up in the air. The FDA recently made a statement saying that, for the time being, they would be allowing the sale of capsules containing Ephedra that did not exceed 10mg per capsule. Currently, this is only a recommendation since the FDA doesn’t have legal control over the herb. For the moment, you can still buy pills with ephedra in the United States, however, that could change at any time.

In December of 2000, the Cantox Report researched 9 controlled studies on ephedra. Each study observed was a minimum of 8 weeks long. These studies looked at heart rate, blood pressure, adverse side effects, and other related indicators. One study revealed that cardiac arrhythmia episodes didn’t occur in subjects given 90mg of ephedra per day vs. a placebo. The Cantox Report concluded that 150mg of ephedrine alkaloids per day was the “lowest observed adverse effect level”. According to their conclusion, the lowest observed adverse effect level is a full 50% higher than the recommended maximum daily dose of 100mg per day of ephedrine alkaloids you will see on ephedra containing diet supplements.

This study also examined the long-term safety and effectiveness for weight loss of an herbal supplement containing Ma Huang and Kola Nut. The results of this six month randomized, double-blind placebo controlled trial were published in the International Journal of Obesity for May of 2002. After a 6 month study, the conclusion was that, “the tested product produces no adverse events and minimal side effects. This is consistent with the known mechanism and action of Ephedrine and Caffeine”.

An estimated 61% of the U.S. adults are over-weight or obese and obesity has reached epidemic proportions in the United States. Obesity continues to be the second leading cause of preventable death. By current estimations, there are 300,000 obesity related deaths per year. Given the current obesity problems in America, the FDA not allowing U.S. citizens to buy pills with ephedra, a diet pill that actually works, seems pretty silly.

Right now, you can still buy pills with ephedra. How long that will last is anyone’s guess. Take advantage of the opportunity while it still exists!

My Supplement Store.com ranked by Inc. Magazine as one of the fastest growing companies in the US for 2007

My Supplement Store.com Ranks No. 793 on the 2007 Inc. 5,000
With Three-Year Sales Growth of 429.8%

My Supplement Store.com also Ranks No. 40 on the 2007 Inc. 5,000 Top 100 Companies in the Retail industry in America

I would first like to give credit where credit is due, to my personal Lord and Savior Jesus Christ; without Him none of this would be possible, all the glory be to our good God. Secondly, I would like to thank each one of you as our valued clients over the past 5 years for making this dream come true.Also in addition to making the Inc. 5000 list and being ranked in the Top 100 for the entire retail industry in the US for 2007 Inc. Magazine has also recognized me as one of the youngest CEO’s in America that made the Inc. 5000 list. Check out the picture below: (I’m the one in the center)

http://www.inc.com/inc5000/
Inc. 5000 Home Page 

http://www.inc.com/multimedia/slideshows/content/5000ceosunder30_pagen_29.html#
Link to the youngest CEO picture 

http://www.inc.com/multimedia/slideshows/content/5000ceosunder30_pagen_36.html#
Lead Off promo image for the Youngest CEO’s List… recognize anyone! 

http://www.inc.com/inc5000/2007/lists/top100-industry-retail.html
Link to the Top 100 List for Retail Industry 

http://www.inc.com/inc5000/2007/company-profile.html?id=200707930
Inc. 5000 Overall rating 

http://www.inc.com/inc5000/articles/20070801/methodology.html
How they chose the Inc. 5000